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Faculty and Staff Research Publications: Trivedi, Vishwa D.

This guide provides information on the publications of Bethune-Cookman University Faculty, Administration, and Staff.

Selected Publications & Other Scholarly Activities

Trivedi, V. Jones, T., Walker, R, Henderson, R., and Kumar, T. K.S. (2016)  “On the role of C-terminal domain of anabaena sensory rhodopsin transducer in unusual stability, ligand and receptor interaction”, Protein Science, 25 [S1 proceedings], 142.

Vogeley, L., Trivedi, V. D. , Sineshchekov, O. A., Spudich, E. N., Spudich, J.L., and Luecke, H. (2007)“Crystal structure of the Anabaena sensory rhodopsin transducer J. Mol. Biol. 367, 741-751.

Bergo, V. B., Ntefidou, M., Trivedi, V. D., Amsden, J. J., Kralj, J. M., Rothschild, K. J., and Spudich, J. L. (2006) “Conformational changes in the photocycle of Anabaena sensory rhodopsin: Absence of the Schiff base counterion protonation signal” J. Biol. Chem 281, 15208-15214.

 Sineshchekov, O. A., Spudich, E. N., Trivedi, V. D., and Spudich, J. L. (2006)  Role of cytoplasmic domain in Anabaena sensory rhodopsin photocycling: vectoriality of Schiff base deprotonation”  Biophys. J.  91, 4519-4527.

 Sineshchekov, O. A., Trivedi, V. D., Sasaki, J., and Spudich, J. L. (2005) “Photochromicity of anabaena sensory rhodopsin, an atypical microbial receptor  with a cis-retinal light-adapted form” J. Biol. Chem. 280, 14663-14668.

Vogeley, L., Sineshchekov, O. A., Trivedi, V. D. , Sasaki, J., Spudich, J.L., and Luecke, H. (2004) “Anabaena Sensory Rhodopsin: A Photochromic Color Sensor at 2.0 Ao”  Science 306, 1390-1393.

Trivedi, V. D., and Spudich, J. L. (2003) “Photostimulation of a Sensory Rhodopsin II/HtrII/Tsr Fusion Chimera Activates CheA-autophosphorylation and CheY-phosphotransfer in vitro” Biochemistry 42, 13887-13892.       

Jung, K.-H*., Trivedi, V. D.*, and Spudich, J. L. (2003)* Equal contributions “Demonstration of a sensory rhodopsin in eubacteria” Mol. Micro. 47, 1513-1522.

Trivedi, V. D., Cheng, S. F., Wu, C.-W., Karthikeyan, R., Chen, C.-J., and Chang, D. K. (2003) “The LLSGIV stretch of the N-terminal region of HIV-1 gp41 is critical for binding to model peptide, T-20” Protein Engg. 16, 311-317

Wu, C. –W., Cheng, S. F., Huang, W. N., Trivedi, V. D., Veeramuthu, B., Assen, B. K., Wu, W. G., and Chang, D. K. (2003) “Effect of alterations of amino-terminal glycine of influenza hemagglutinin fusion peptide on its structure, organization and membrane insertions”  Biochim. Biophys. Acta 1612, 41-51.

Jung, K.-H., Spudich, E. N., Trivedi, V. D., and Spudich, J. L. (2001) “An archaeal photosignal-transducing module mediates phototaxis in Escherchia coli” J. Bact. 183, 6365-6371.

 Chang, D. K., Cheng, S. F., and Trivedi, V. D. (2001)“Conformation and interaction with the membrane models of amino-terminal peptide of influenza virus hemagglutinin HA2 at fusion pH” Arch. Biochem. Biophys. 396, 89-98.

Chang, D. K., Trivedi, V. D., Cheng, S. F., and Francis, S. (2001) “The leucine zipper motif of the envelope glycoprotein ectodomain of human immunodeficiency virus type 1 contains conformationally flexible regions as revealed by NMR and circular dichroism studies in different media” J. Peptide Res. 57, 234-239

Trivedi, V. D., Yu, C., Veeramuthu, B., Francis, S., and Chang, D. K. (2000) “Fusion induced aggregation of model vesicles studied by dynamic and static light scattering”.Chem. Phys. Lipids 107, 99-106.

Chang, D. K., Cheng, S. F., Trivedi, V. D., and Yang, S. H. (2000) “The amino-terminal region of fusion peptide of influenza virus hemagglutinin HA2 inserts into sodium dodecyl sulfate micelle with residues 16-18 at the aqueous boundary at acidic pH. Oligomerization and conformation flexibility”. J. Biol. Chem. 275, 19150-19158.

Samuel, D., Kumar, T. K., Ganesh, G., Jayaraman, G., Yang, P-W., Chang, M-M., Trivedi, V. D., Wang, S-L., Hwang-K-C., Chang, D. K., and Yu, C. (2000) “Proline inhibits aggregation during protein refolding”. Protein Sci. 9, 344-352.

Chang, D. K, Cheng, S. F., Trivedi, V. D., and Lin, K. L. (1999) “Proline affects oligomerization of coiled-coil by inducing a kink in a long helix”. J. Struct. Biol. 128, 270-279.

Chang, D. K, Cheng, S. F and Trivedi, V. D. (1999)  "Biophysical characterization of the structure of the amino-terminal region of gp41 of       HIV-1: Implications on viral fusion mechanism".  J. Biol. Chem. 274, 5299-5309.

Trivedi, V. D., Raman, B., Ramakrishna, T., and Rao, C.M. (1999) "Detection and assay for proteases using eye lens beta-crystallin as substrate".  J. Biochem. Biophys. Methods 40, 49-55.

Trivedi, V. D., Raman, B., Ramakrishna, T., and Rao, C.M. (1999) "Detection and assay for proteases using eye lens beta-crystallin as substrate". J. Biochem. Biophys. Methods 40, 49-55.

Trivedi, V. D., Vorum., H.,Honore, B., and Qasim, M. A. (1999) "Molecular basis of Indomethacin-human serum albumin interaction". J. Pharm. Pharmacol. 51, 591-600.

Rao, C. M., Raman, B., Ramakrishna, T., Rajaraman, K., Ghosh, D., Dutta, S., Trivedi, V. D. and Sukhaswami, M. B. (1998) "Structural perturbation of alpha-crystallin and its chaperone like activity".  Int. J. Biol. Macromol. 22, 271-281

Trivedi, V. D., Raman, B., Ramakrishna, T., and Rao, C. M. (1997) "Co-refolding denatured-reduced hen egg white lysozyme with acidic and basic protein". FEBS Lett. 418, 363-366.

 Trivedi, V. D., Saxena, I., Siddiqui, M. U., and Qasim, M. A. (1997) "Interaction of  bromocresol green with different serum albumins studied by fluorescence quenching". Biochem. Mol. Biol. Int. 43, 1-8.

 Trivedi, V. D. (1997)  "On the role of buried lysine residues in bromophenol blue-albumin interaction".  Ital. J. Biochem. 46, 67-73.

Tayyab, S. and Trivedi, V. D. (1995) "Binding of bilirubin to goat serum albumin: determination of binding constant".  Biochem. Edu. 23, 98-100.

Other Scholarly Activities:

Have attended several conferences symposiums and presented the work as invited speaker in US and abroad. Also served as chapter reviewer for biochemistry text books and researcher journal reviewer to “Process Biochemistry:  an application-orientated research journal by ELSEVIER Publisher. Developed and wrote College Chemistry Lab manual along with other interactive learning tools.

Library Tags

Tags: SchoolofSEM ,  curefacultymentor2017

Vishwa D. Trivedi, Ph.D

                 Dr. Vishwa D. Trivedi

Assistant Professor, Chemistry/Biochemistry

CURE FACULTY MENTOR 2017

Office Location: Rabie J. Gainous Science Annex/Observatory #224
Office Phone: 386-481-2688
Email Address: trivediv@cookman.edu

Education:

  • Instructor- Center for Membrane Biology, Department of Biochemistry and Molecular Biology, Univ. Texas Medical School-Houston, Texas.

  • Research Fellow Department of Microbiology and Molecular Genetics, Biochemistry and Molecular Biology, Univ. Texas Medical School-Houston, Texas.

  • Post Doctoral Fellow Institute of Chemistry, Academia Sinica, Taipei, Taiwan

  • Post Doctoral Fellow Center for Cellular and Molecular Biology, India (Department of Biotechnology, Fellow)

  • Ph.D. [Biochemistry] J. N. Medical College, Aligarh M University, Aligarh, India
  • M. Phil. [Clinical Biochemistry] J. N. Medical College, Aligarh M University, Aligarh, India
  • M.Sc. [Biochemistry] School of Life Science, Aligarh M University, Aligarh, India
  • B. Sc. [Hons.], Chemistry major, School of Science, Hons.], Chemistry major, School of Science, Aligarh M University, Aligarh, India 

 

Image result for pdf image    Dr. Trivedi's Research Card

Image result for researchgate   Dr. Tivedi's ResearchGate page  - full-text of many of his articles

 

Current research interests:

[A] Microbial Sensory Rhodopsin Mediated Signaling:

Cloning of newfound microbial sensory rhodopsins, Overexpression, purification and functional characterization of these sensory receptors. Development of “in vitro” assay to explore receptor activation and signal transduction via cognate transducer protein by regulating downstream histidine kinase and response regulator. Ligand binding and localization of receptor and/or transducer protein to explore protein-protein interaction.

Role of phospholipids and chaperones as an aid in overexpression, stabilization and functional assembly of membrane receptors with an emphasis on channel rhodopsin. Structure-function relationship of these sensory molecules and their transducer involved in signaling pathway to outline molecular basis of receptor mediated signaling, Structural studies to correlate conformation-functional relationship of receptor transducer via protein-protein interaction.

[B] Viron Mediated Membrane Fusion

Conformational-structural features of HIV-1 and influenza fusion domain, Role of oligomerization on membrane fusion, Design the methodology of model membrane fusion and inhibition.

[C] Molecular Basis of Cataract and Hyperbilibuninemia

Role of protein folding/cofolding and human disease, Functional features of α-crystallin as molecular chaperone. Molecular basis of interaction and displacement of bilirubin by serum albumin by broad spectrum of drugs.

 

Current Research Support:

National Institute of General Medical Sciences, NIGMS, NIH: Support of Competitive Research, SCORE, SC-3 Program project entitled “Ligand Binding and Signaling State of Anabaena Sensory Receptor Transducer”: Principal Investigator, PI.

1SC3GM113803-01 May 01, 2015-Jan. 31, 2019

Total cost: $379,000

ResearchGate Page

Image result for researchgate

Many of the articles listed on this page can be downloaded from Dr. Trivedi's ResearchGate page.